Tubulin study

Investigation of tubulin aspects of cerebral protein 10-
By Mark McGary
Rather interesting observation details of the Plasmodium f. intersection via residue occur at the intersection cerebral protein 10 and plasmodium with outlier indications observed in ades e. at FKBP-type peptidyl-prolyl cis-trans isomerase [Aedes aegypti]

The structural component of the gene has rather interesting features, of which high acidic mole observation is a natural first inquiry. However, the high mole indicator at position 2 is useful to probe via selkov the causal nature of interior differentation in homo sapiens with the ceberal element premised to be directly attacked in the plasmodium presentation of case.
Of particular observation inference is a small, succinct residue group at :ESDNERDSDKESEDGEDEVSCETVK observed in human and the PREDICTED: regulator of microtubule dynamics protein 3-like [Loxodonta africana] 61.7 84.8 33% 5e-08 100% XP_003418704.1
It is with some rather extensive view within the larger tubulin assortment as regards residue that I can begin to make rather instant assessment of the high mole relief observed of prominence.
The renal tissue indication as well as the recent tubulin reversal within a oncology study deminstrates to the author a fundamental association of this gene residue as latent to the attack by pathway or schema…of several pathogen associations as well as observed oncological impacts.
Let us examine the repeat regionality of conservation in homo sapiens and hence move the the loxadonta for contrasting viewpoint.
1578 bp mRNA linear MAM 25-AUG-2011 DEFINITION PREDICTED: Loxodonta africana regulator of microtubule dynamics protein 3-like (LOC100662607), mRNA. ACCESSION XM_003418656 VERSION XM_003418656.1 GI:344293993 KEYWORDS RefSeq. SOURCE Loxodonta africana (African savanna elephant) ORGANISM Loxodonta africana

Homo Sapiens:
taxon:9606″ /tissue_type=”Brain” Protein 1..470 /product=”cerebral protein-10″ CDS 1..470 /gene=”hucep-10″ /coded_by=”AB000782.1:1..1413″ /inference=”non-experimental evidence, no additional details recorded” /note=”HUCEP-10″ ORIGIN 1 msrlgalgga raglglllgt aaglgflcll ysqrwkrtqr hgrsqslpns ldytqtsdpg 61 rhvmllravp ggagdasvlp slpregqekv ldrldfvlts lvalrrevee lrsslrglag 121 eivgevrchm eenqrvarrr rfpfvrersd stgsssvyft assgatftda eseggyttan 181 aesdnerdsd kesedgedev scetvkmgrk dsldleeeaa sgassaleag gssgledvlp 241 llqqadelhr gdeqgkregf qlllnnklvy gsrqdflwrl araysdmcel teevsekksy 301 aldgkeeaea alekgdesad chlwyavlcg qlaehesiqr riqsgfsfke hvdkaialqp 361 enpmahfllg rwcyqvshls wlekktatal lesplsatve dalqsflkae elqpgvskag 421 rvyiskcyre lgknsearww mklalelpdv tkedlaiqkd leelevilrd //

Recently, I have been rather interested in direct conserved mutation in neonate as pathogenesis, and this combined locus seems to rather make sense as an avenue to discern mutation causality.
I suspect the cocci residues are involved, but unraveling the avenues by selkov should present the most factual intersections to be observed.
Why? Because the Selkov determinants of high mole indication, are now oraganized into single endpoint indicator. This method is leading to topological model of gene signal. *ie. on – off.
mutational scarring of needed conservation for normal neonatal development seems to be within reach, and of course presents the implication of develomental methods by conformational relief as a research viewpoint.
The tubulin aspect seems succinct via observational intersection in larger cranial observation seen in loxodanta and homo sapiens.

The author simply needs to take advantage of this implied organizational resource to the sets of protein residue in view as pathogenicity…..and aberant conservation to presentation in case.

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single point mutation in virus

A model of spore germination insertion to viral residue via paenibacilli
by Mark McGary

Designing a mollecular toolbar specific to viral mutation adventure is an interesting challenge. Here, the paenibacilli residue uptake to viral species by insertion and conservation is examined in short motief via selkov and frame model.
A descriptor of point mutation may impact future forecast of influenza residue compromising immune response via a mutli species viewpoint, and have the retrospective view of identifying filo virus origin, thus premising stratagies for immune response.
The emergence of selkov as a re-assortment pre blast challenge as a working model is surprising in it variability to extract mutispecies alignment, with the addition of a frame viewer as regards internal observed reside by pattern a method to return elegant and small relief to complex data, as a data mining mode not observed in literature.
The results to pan troglodite, gorilla and homo sapiens a predective model in the HIV study, for example. Following model with insertion via shistisome was also observed as causal within an Echo E-30 relief, premising availability to demonstrate a porcine enterovirus uptake, insult specific to gut.
Working to fundamental single point mutation seems a coherent and succinct model to premise viral mutation as an addative reaction descriptor to advance formulary and immune respone studies.

Homo sapiens gene BAG 65521.1

Feline corona virus to mammal (mus muscularis)

Observed pattern identity with a premised anchor and high mole process (index).

Here is an interesting observation post kidney process (residue of gene in pteropus a,
subsequent selkov, relaxed fit observational to corona and mammal.
An excellent target regionality for viral process via. mammal and known physio-dynamic of renal observation…interestingly, observed post cell wall anchor and superoxide dismutase as seen in homo sapiens BAG 65521.1. The observer should notice the idenity observed in pattern. shown below.

AFH58022 721 CMPTCSDTSILGNVKIMLGNGVKVICDGCHSLANRLTVNYSKLCDTARKDIEIGGIPFSTFKTPSSSFIDMKDAIYSVVE 800 AFH58023 721 CMPTCSDTSILGNVKIMLGNGVKVICDGCHSLANRLTVNYSKLCDTARKDIEIGGIPFSTFKTPSSSFIDMKDAIYSVVE 800 XP_006540824 1 —-MFATEVIGIGRDWPWPNLTALFLFLQSLISTQTLV——GASSTIQF—-FFSEALMGQNFQEVELENYEP-Q 65 AFH58022 801 YGEAFSFKTASVPVTNSGTITTDDWSDPILLEPADYVEPKGNGDVIVIAGYTFYKDEDDHFYPYGSGMVVQKMYNKMGGG 880 AFH58023 801 YGEAFSFKTASVPVTNSGTITTDDWSDPILLEPADYVEPKGNGDVIVIAGYTFYKDEDDHFYPYGSGMVVQKMYNKMGGG 880 XP_006540824 66 PGDLFLFKLQTPKAQWCG—————AHVGVYCGQGEIIHFEGRTSNQNGVQTFLGYCEGVVCKQGHRAL— 127 AFH58022 881 DKSVSFSDNVIVKEIKPVTRVRLEFEFRQCKVVTQVLEKVIGTKYKFTGTTWDEFEDSISEELDRIFDTLAEQGVELEGY 960 AFH58023 881 DKSVSFSDNVIVKEIKPVTRVRLEFEFRQCKVVTQVLEKVIGTKYKFTGTTWDEFEDSISEELDRIFDTLAEQGVELEGY 960 XP_006540824 128 —————————QRSRQLWRVLRRRGGVD——————-PRVLESRVREAMDNDPP 161 AFH58022 961 FIYDTCGGFVHSTQMVLASHSMILTQLLMTKAEVSAKNDPWAVAVDEQEAEQPKHSFSPFRTTDLNGKIILKQQDNNCWV 1040 AFH58023 961 FIYDTCGGFVHSTQMVLASHSMILTQLLMTKAEVSAKNDPWAVAVDEQEAEQPKHSFSPFRTTDLNGKIILKQQDNNCWV 1040 XP_006540824 162 PYHPTSSNCVHFALNLLGMDSMSMDRNLTSD————————————————- 192